Vyas Lab

Investigating how hormonal changes during pregnancy shape long-term cardiovascular health, our center explores the molecular mechanisms linking gestational hyperandrogenism and exposure to endocrine-disrupting chemicals with adverse maternal and fetal cardio-metabolic outcomes. By integrating large animal models with cellular and molecular biology, we aim to uncover pathways that predispose offspring to cardiovascular disease and identify strategies for prevention and treatment. Our work advances the developmental origins of health and disease framework, driving innovation in early-life interventions.