Infectious Diseases | Research

Our Pediatric Infectious Diseases faculty are recognized for outstanding research related to childhood infections, organized generally along these major lines:

Human viral discovery and viral biology:
Gregory Storch, MD - Viral discovery in children with fever and respiratory illness
Kristine Wylie, PhD - Microbial genomics, including the maternal-fetal virome
Andrew Janowski, MD - Pathogenesis of astrovirus infections; viral discovery in human encephalitis

Molecular pathogenesis of bacterial infections:
David Hunstad, MD - Gram-negative bacterial infections, particularly Escherichia coli urinary tract infections
David Rosen, MD, PhD - Molecular pathogenesis and antimicrobial resistance in Klebsiella pneumoniae

Molecular diagnosis of infectious diseases:
Gregory Storch, MD - molecular tests for the detection of multiple viruses and noncultivatable bacterial pathogens; integration of host transcriptional signatures into infectious diseases diagnostics

Basic mechanisms in immunology and hematopoiesis:
S. Celeste Morley, MD, PhD -  molecular effectors of leukocyte maturation and motility; mitochondrial function in pathogen defense
Anthony Orvedahl, MD, PhD - autophagy in immune responses to sepsis and viral infections
Abby Green, MD - DNA damage responses in leukemia and in control of viral infections

Patient-oriented and translational research:
Stephanie Fritz, MD, MSCI - epidemiology and transmission of community-associated Staphylococcus aureus
Jason Newland, MD, MEd - pediatric therapeutics and antimicrobial stewardship; community use of antimicrobials and COVID diagnostics
Mimi Kao, MD, Jason Newland, MD, MEd, and Rachel Orscheln, MD - clinical trials of new antimicrobials and vaccines in children

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