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Unlocking the mechanisms of immune regulation to combat severe inflammation and cytokine storm syndromes our lab investigates how immune responses are controlled to prevent fatal reactions. We use in vitro and in vivo approaches to identify key genes and pathways, focusing on autophagy and its role in protecting macrophages and preventing cytokine storm. Our goal is to develop host-directed therapies for infectious and inflammatory disorders.

Research profile

Co-hosts Katherine Rivera-Spoljaric, MD, and Philip Abraham, MD, from Washington University School of Medicine in St. Louis and co-directors of the Department of Pediatrics Office of Faculty Development provide tips on avoiding burnout in the clinical space. Invited guests will join Katherine and Phil every episode to discuss their personal experiences on key wellness topics.

Strengthening connections across WashU Medicine, OUTmed fosters belonging while providing education and resources to support individualized patient care. Through networking, mentoring and advocacy, the program creates opportunities for staff, students, trainees and faculty to engage and thrive — regardless of identity.