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Decoding the genetic causes of rare childhood diseases through cutting-edge genomics, our lab is committed to uncovering the molecular basis of severe conditions and birth defects in infants and children. Using advanced sequencing technologies such as whole exome and genome sequencing, RNASeq and gene expression profiling, we identify pathogenic variants and investigate their functional impact. Our focus on disorders of pulmonary surfactant metabolism, including genes like SFTPB, SFTPC, ABCA3 and NKX2-1, aims to reveal new therapeutic targets and improve outcomes for children facing life-threatening respiratory diseases.

Wambach research profile
Cole research profile

Providing a warm and engaging environment, the Washington University Family Learning Center offers high-quality child care and preschool programs managed by Bright Horizons. Serving faculty, staff, graduate students and local families, our dedicated teachers inspire learning, build confidence and support every stage of your child’s development.

Uniting physicians, attorneys, students and parents, WUMCHA creates a supportive community for those navigating medical careers and relationships. With members from seven countries and 24 states representing more than 50 specialties, we understand the unique challenges of balancing professional and family life. Through seasonal events and special interest groups, we foster connection, friendship and shared experiences.

Focusing on awareness and skill-building, our training programs help WashU Medicine community members foster respect, address bias, and create inclusive environments for learning, working, and patient care. Sessions are offered virtually or in person, with hybrid options available by request.

Offering priority scheduling and reduced copays or coinsurance, WashU Direct connects employees and dependents with WashU Medicine’s network of more than 2,100 providers. Most initial appointments are available within 14 days, ensuring timely access to exceptional care while maximizing your health plan benefits.

Creating a community rooted in fairness and respect, WashU’s Equity, Diversity & Inclusion initiatives aim to ensure that all voices are valued. By fostering diverse perspectives and collaborative engagement, these efforts strengthen the university’s commitment to equity and belonging for every member of our campus.

Connecting patients with expert physicians, nurse practitioners and physician assistants, WashU Medicine offers primary care alongside its renowned specialty services. Supported by advanced technology and specialist consultation, our network — including Washington University Clinical Associates — provides high-quality care at convenient locations throughout the St. Louis area.

Committed to excellence in patient care and medical discovery, WashU Medicine physicians provide comprehensive specialty services for patients of all ages. Our full-time specialists combine clinical innovation with compassionate care to improve health and well-being across every stage of life.

Serving as the central hub for academic and clinical events, the WashU Medicine calendar connects faculty, staff, trainees and the broader community with opportunities to learn, collaborate and engage. From grand rounds and research seminars to workshops and special programs, this calendar makes it easy to stay informed and participate in the vibrant educational and scientific life of the School of Medicine.

Highlighting discoveries and innovations across disciplines, Research News showcases the groundbreaking work of Washington University in St. Louis. From transformative studies and clinical breakthroughs to emerging technologies and collaborative initiatives, this platform keeps you informed about the research shaping science, medicine and society.