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The Center for Advanced Medicine serves as the outpatient clinic for many adult specialties at WashU Medicine. Patients receive multidisciplinary consultations, diagnostic services, medical treatments, same-day surgeries and other support — all in one convenient location.

This building is home to the Alvin J. Siteman Cancer Center, an internationally recognized leader in cancer treatment, research, prevention, education and community outreach. Siteman is the only cancer center in Missouri — and within a 240-mile radius of St. Louis — to hold the Comprehensive Cancer Center designation from the National Cancer Institute and membership in the National Comprehensive Cancer Network.

The center brings together the expertise of more than 350 WashU Medicine physicians and research scientists, caring for over 7,000 newly diagnosed cancer patients and 32,000 follow-up patients each year. These specialists collectively manage nearly $150 million in cancer research and training grants, driving innovation and advancing cancer care.

Facilitating top-quality clinical research, this center supports WashU Medicine investigators with comprehensive administrative and clinical research services from initial proposal development through study close-out. Our mission is to streamline processes, ensure regulatory compliance and provide expert guidance, enabling researchers to focus on advancing discoveries that improve patient care.

Advancing research at the intersection of metabolism and immune function, our center focuses on musculoskeletal, kidney and gastrointestinal disorders, including microbiome-related conditions and diseases driven by metabolic and immune dysregulation. Through collaborative science and innovative approaches, we aim to uncover mechanisms that shape health and disease, translating discoveries into strategies that improve patient outcomes and quality of life.

Uncovering the molecular roots of immune disorders to improve care, the WashU Medicine Center for Pediatric Immunology is dedicated to advancing outcomes for children with inborn errors of immunity. By providing robust scientific infrastructure and leveraging cutting-edge technologies, the center drives discovery of genetic mechanisms that inform diagnosis and therapy. Through collaboration among clinicians, scientists and trainees, we aim to transform understanding and treatment of pediatric immune diseases.

Investigating the mechanisms behind childhood respiratory illnesses to improve health and well-being, our center is dedicated to reducing the global burden of pulmonary diseases such as pneumonia and asthma. By advancing research through innovative protocols and translating discoveries into clinical care, we aim to enhance diagnostics, develop effective treatments and ultimately save lives. Through collaboration and cutting-edge science, we strive to create a healthier future for children everywhere.

Bringing together researchers and patient communities to accelerate breakthroughs, our center fosters collaboration in rare and genetic disease research. By uniting WashU Medicine experts with individuals affected by rare conditions, we create a dynamic network that drives innovation and speeds the path to new therapies. Through shared knowledge and resources, we aim to transform understanding and treatment, ultimately improving lives.

Providing comprehensive training in child abuse pediatrics, this three-year ACGME-accredited fellowship leverages the clinical resources of the nationally renowned St. Louis Children’s Hospital and the academic and research opportunities offered by WashU Medicine.

Driving impact through programs and partnerships, Child Care Aware® of Missouri supports families and providers with workforce development, business resources, advocacy and policy initiatives. Through efforts like Child Care Keeps Missouri Working℠, the organization helps businesses address recruitment and retention challenges caused by limited access to quality child care.

Improving outcomes for children with chronic illnesses through research and education, the Child Health and Education Lab focuses on conditions such as Sickle Cell Disease and brain tumors. Led by Allison King, MD, MPH, PhD, our team investigates how environmental, cognitive and psychosocial factors influence health and development. Through partnerships like the Heartland and Southwest Sickle Cell Disease Network, we work to enhance care and quality of life across an eight-state region, while advancing strategies for assessment, transition and long-term support.

Research profile

Accelerating the pace of discovery, the Children’s Discovery Institute (CDI) represents a transformative partnership between St. Louis Children’s Hospital and WashU Medicine, dedicated to redefining pediatric research and delivering innovative therapies for previously untreatable conditions. Through expanded donor-funded initiatives in gene and cell-based therapies, infectious disease and pediatric immunology, CDI fosters collaboration across disciplines to drive faster scientific breakthroughs and improve outcomes for children everywhere.