Cellular housekeeping process implicated in fatal neurological disorder (Links to an external site)

A study from Washington University School of Medicine in St. Louis shows that as patients age, Huntington's disease impairs autophagy, which eliminates waste from cells. Shown at left are neurons transformed from skin cells of a young patient with pre-symptomatic Huntington's disease. On the right are neurons transformed from skin cells of an older patient with symptomatic Huntington's; these cells are sparse because the aging process impairs autophagy, leading to cell death.

Huntington’s disease, a fatal, inherited neurodegenerative condition, is caused by a genetic error present at birth, though its symptoms often don’t begin until middle adulthood. Scientists at Washington University School of Medicine in St. Louis have been trying to understand how the aging process triggers the onset of symptoms, with the expectation that such knowledge […]

First of its kind DeSanto-Shinawi Syndrome clinic takes place at St. Louis Children’s Hospital

Marwan Shinawi, MD, feels Leo's lymph nodes during first-ever DeSanto-Shinawi Syndrome clinic on Sept. 29, 2022, at St. Louis Children's Hospital.

A first of its kind clinic has parents and medical professionals alike excited. The inaugural DeSanto-Shinawi Syndrome clinic took place on Sept. 29-30 at St. Louis Children’s Hospital. It was the first clinic of its kind in St. Louis for the syndrome that was described by Washington University pediatrician Cori DeSanto, MD, and Washington University […]

Testing Inclusivity and Innovation Benefits All (Links to an external site)

Masked children in classroom

When the COVID-19 pandemic struck in the spring of 2022, students and staff at schools that serve children with intellectual and developmental disabilities (IDD) were left stranded. These students and staff faced unique circumstances because they could not always follow the CDC guidance on masking, testing, and social distancing due to the nature of these […]

55 Pediatrics faculty recognized on 2022 Castle Connolly Top Doctors® List

2022 Peds Top Docs

The Department of Pediatrics is proud to announce 55 of our faculty members have been selected for the 2022 Castle Connolly Top Doctors® List. Our physicians work hard each and every day to provide their patients with unmatched care. Each year, Castle Connolly uses a merit-based system to select board-certified physicians for its Top Doctors® […]